THE EFFICACY OF PHYSIOLOGICAL SPERM SORTING IN ADDITION TO MORPHOLOGICAL SORTING

Selection of spermatozoa is one the most important factors that influence embryonic development and clinical outcome in intracytoplasmic sperm injection (ICSI). Intracytoplasmic morphologically selected (IMSI) a technique selects only according to their features under high magnification. However, there another selection uses hyaluronic acid (HA) select physiologically mature (HA-ICSI). The purpose this study investigate efficacy physiological sorting addition morphological sorting, how could contributes subsequent outcomes. Study 1: A total 658 (MII) oocytes derived from large follicles obtained letrozole cycle were enrolled between April 2017 May 2020. Sperm using HA was performed with SpermSlow™ (ORIGIO). normal fertilization rates, abnormal egg degeneration cleavage blastocyst formation freezing good quality rates at compared two groups (339 IMSI group (April 2018) 319 HA-IMSI 2018 2020)). 2: Clinical pregnancy (CPR), live birth (LBR), abortion day 2 fresh stage embryo transfer (d2ET) group. 128 patients (age 34–40 years) out 225 37.1± 4.1 years ) who underwent d2ET first treatment January December 2019 enrolled. Written informed consent all participants. participants <40 age significantly higher (73.3% vs. 58.0%, p<0.05) than >40 lower (0.7% 5.2%, Other parameters also showed favorable trends group, but not statistically significant. CPR LBR (18.2% vs 34.2%, p<0.05 14.6% 32.9%, respectively) There no significant differences rates. Blastocyst suggests effect more remarkable when oocyte guaranteed.